Study Finds Mesothelioma May Be Caused Partly Due to Genetics

A new study financed by a section of the National Institutes of Health has made the first potential connection to an individual’s genetics and susceptibility to eventually developing deadly asbestos illnesses such as mesothelioma.

The study, which was recently published online in Nature Genetics, found evidence that people with BAP1 gene mutations may have an increased chance of developing multiple cancer types such as mesothelioma, breast, ovarian, pancreatic and renal cancers. The study highlighted two U.S. families with members who have the BAP1 gene mutation. Both families also have “a high incidence of mesothelioma.”

“This discovery is a first step in understanding the role of the BAP1 gene and its potential utility when screening for mutations in those at high risk,” said Dr. Michele Carbone, study co-leader and director of the University of Hawaii Cancer Center. “Identifying people at greatest risk for developing mesothelioma, especially those exposed to dangerous levels of asbestos and erionite worldwide, is a task made easier by virtue of this discovery.”

Dr. Joseph R. Testa, another study co-leader and the Carol and Kenneth E. Weg chairman in Human Genetics at Fox Chase Cancer Center, said the study was the first to “demonstrate that individual genetic makeup can greatly influence susceptibility to mesothelioma.”

While only a first step, the discoveries noted in this study could one day lead to fundamental progress in mesothelioma care. Thanks to Drs. Carbone and Testa and their crew for the hard work. We hope this is just the beginning of bigger breakthroughs to come.

Living with the day-to-day hardships of mesothelioma – whether it is you or a loved one who has been diagnosed with the illness – is both emotionally and financially taxing. If you feel that a company or former employer may be responsible for the asbestos exposure that led to an illness, contact a mesothelioma attorney to learn about filing amesothelioma lawsuit.

Mesothelioma

What are the Most Common OB Mistakes

Medical liability cases against obstetricians and other doctors who participate in the birthing process are most often spurred by errors in clinical judgment, miscommunication between doctors, and technical mistakes.

All of these errors can potentially result in a birth injury occurring that may remain with the newborn child for their entire lives.

According to a study released this month by CRIGO Strategies that analyzed more than 800 OB medical liability cases filed between 2005 and 2009, the three most common allegations in the lawsuits were as follows: Delayed treatment of fetal distress, improper execution of vaginal delivery, and improper management of pregnancy.

“Obstetrics has some unique vulnerabilities, most often involving situations in which a sequence of errors or oversights cascade into a crisis that can put mother and baby in jeopardy,” said Robert Hanscom, CRIGO’s senior vice president.

Obstetrician errors can result in a number of birth injuries that can affect the mother and/or the child being born. Among the more serious birth injuries a newborn can suffer from is cerebral palsy, which can affect a newborn for the rest of his or her life and often relegate them to a wheelchair and constant medical care.

If you or your child was born with a birth injury that can be attributed to medical error, such as cerebral palsy, there may be legal options available to you. Contact a birth injury attorney at Sokolove Law today to learn about your options regarding a lawsuit against the doctors who caused your injury.

Birth Injury

Taking Action on National Mesothelioma Awareness Day

Aside from legal ads on TV, many Americans don’t know what asbestos is or where it can be found, let alone that exposure to this dangerous material can result in the development of an asbestos-related cancer such as mesothelioma. In fact, mesothelioma occurs in such a small number of patients – it’s estimated that only 2,500-3,000 new patients are diagnosed every year – that the disease is often referred to as an orphan disease. And while new mesothelioma treatments can alleviate symptoms and improve a patient’s quality of life, to date there is no proven cure for the disease.

Perhaps most troubling is the fact that despite these known health risks, asbestos is still not banned in the United States and is manufactured and used every day.

But you can help change this. There are a number of easy ways for you to join the fight to ban asbestos and beat mesothelioma forever, and it all begins with one simple goal: raising awareness.

Each year, the Mesothelioma Applied Research Foundation (MARF) recognizes September 26 as National Mesothelioma Awareness Day in order to educate the public about the dangers of asbestos exposure and raise much-needed financial support for research towards improved treatments of the disease. The first Mesothelioma Awareness Day was started in 2004 by a group of volunteers and every year since has been larger and more widespread.

Want to participate, but don’t know where to start? Here are some ideas:

  • Write a letter to Congress urging them to ban asbestos. We have a pre-written letter on our homepage you can sign and send digitally in minutes. (Yes, your representatives really receive them and sometimes they’ll even write you back!)
  • Spread the word! You can click the Facebook and Twitter buttons on the top or bottom of this page to easily share the news about Mesothelioma Awareness Day with your friends.
  • Join MARF’s social media campaign. They have ready-to-use facts and updates for you to share online.
  • Plan or attend a fundraising event. You can check MARF’s event calendar to see if there’s anything planned in your area, and if there isn’t, they have otherideas how you can become involved – both on 9/26, as well as throughout the year.
  • Make a donation to a non-profit organization like MARF or the Asbestos Disease Organization (ADAO).
  • Check out the Mesothelioma Resource Center’s list of ways to raisemesothelioma awareness, which include contacting local news outlets, meeting local government leaders, fundraising and more.

Whether it’s the click of a mouse or a dollar in a donation jar, you CAN make a difference on National Mesothelioma Awareness Day. By raising awareness, we can save lives through safety education and prevention, as well as gaining support for the movements to ban asbestos and secure additional funding for improved treatments.

So take action and spread the word! Together, we can ban asbestos and beat asbestos-related diseases like mesothelioma.

Mesothelioma

Ten Surprising Asbestos-Containing Products

With Mesothelioma Awareness Day coming up on Monday, September 26th, we thought it apt to highlight the top ten products we were surprised to find that are still being manufactured today with the use of the known carcinogen, asbestos. Asbestos exposure has long been known to cause mesothelioma as well as other cancers and diseases. Mesothelioma Awareness Day is an annual day devoted to raising awareness about mesothelioma and raising funds for mesothelioma research.

In this post — the first in a series of Mesothelioma Awareness Day posts designed to help raise awareness – we present our top ten asbestos-containing products to be aware of:

1. Baby Powder

Baby powder? Baby powder!

Baby powder and other adult cosmetic powders and talcum powders often contain talc. The International Agency for Research on Cancer (IARC) classifies talc that contains asbestos as “carcinogenic to humans” and talc not containing asbestos as “not classifiable as to carcinogenicity in humans.

2. Cigarette Filters

As if smoking cigarettes wasn’t already bad enough, asbestos has been known to be present in the filters.

3. Hair Dryers

Check with the manufacturer of your specific model, as some hair dryers have asbestos-based insulators.

4. Mittens

Are your hands really that cold? Some fire or heat-proof mittens have linings that contain asbestos.

5. Yarn

Typically, you don’t have to worry about the yarn you’re using to knit a scarf, unless it’s known to contain heat-proof threads, which contain asbestos.

6. Popcorn Poppers

As with hair dryers, most small electronics and appliances manufacturers have discontinued the use of asbestos. If yours is an older model or if you have concerns, contact the manufacturer.

7. Brake Pads

Many automotive parts are still manufactured with asbestos today, especially brake pads, to help prevent overheating.

8. Cork Board

If you have an old cork board and you can’t verify its safety with a manufacturer, think twice before tacking up your next picture or note.

9. Duct Tape

Many electrical tapes contain asbestos to help prevent melting or catching fire.

10. Rope

Although many ropes are asbestos-free, some that are heat or fire resistant do contain asbestos.

When asbestos fibers are inhalable, they are breathed into the lungs where the microscopic fibers embed into the tissue and accumulate. The inhalation of asbestos fibers is the leading cause of mesothelioma.

Speak to an Asbestos Attorney Today

For those who have been diagnosed with mesothelioma cancer that can be linked to asbestos exposure caused by a product or former employer, you may be entitled to financial compensation. Contact an experienced mesothelioma attorney to learn more about your rights, and to see if pursuing a mesothelioma settlement is in your best interest.

Asbestos

Vaginal Lawsuit Statement

Vaginal Lawsuit : Incontinent nulliparous women have been shown to have a quantitative and qualitative reduction in the collagen content of their tissues12where no evidence of neuromuscular damage exists. In the Nuns Study, 50% postmenopausal) nuns complained of UI; 30% of these complained of stress incontinence, 24% had urge incontinence and 35% had mixed symptoms. Therefore, in the absence of obstetric trauma, UI is more commonly seen to be of a stress rather than an urge type It is possible that neuromuscular damage and connective tissue deficiency are co-contributors in the aetiology of UI. Among primigravid women, those with excessive bladder-neck mobility have the highest risk of postpartum urinary incontinence.14 It seems likeLy that connective tissue damage is a ‘prerequisite’, and that neuromuscular damage contributes to the aetiology of USI.

Thirty-seven percent of women notice a deterioration in symptoms prior to menstruation.15 Furthermore, progestogens have been associated with an increase in irritative bladder symptoms1617 and urinary incontinence in those women taking combined hormone replacement therapy.18 The incidence of DO in the luteal phase of the menstrual cycle may be associated with raised plasma progesterone following ovulation – progesterone has been shown to antagonize the inhibitory effect of oestradiol on rat detrusor contractions.19 This may help to explain the increased prevalence of DO found in pregnancy.

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Intervention may be preventive. Elective caesarean section may prevent neuromuscular damage9 but may not prevent postnatal UI.4 Rather, antenatal pelvic-floor-muscle training is effective in reducing the incidence of post­partum UI.8Postpartum pelvic-floor-muscle training is effective in reducing the incidence of UI at one year. Follow-up of a cohort of women who delivered in 1994 showed that 31.8% of those dry pre­pregnancy are now incontinent.21 Women with increased bladder-neck mobility have an increased incidence of stress incontinence at 14 weeks postpartum, even if there is no pre­existing symptomatology.14 However, onset of UI prior to the initial pregnancy is the best predictor of incontinence 5-7 years later.21 Caesarean section remains protective, but less so than at three months postpartum, with a relatively greater effect with increasing parity. The effect is particularly pronounced if the caesarean section is undertaken prelabour.

Information from other sources on Vaginal Lawsuit

‘Routine’ episiotomy was introduced in the UK in the 18th Century and has been advocated to prevent severe perineal tears and preserve sexual function. Review of five randomized controlled trials of the use of routine and selective episiotomy reveals that sexual function is poorer in the routine group, with no difference in the prevalence of UI and no difference in pelvic-floor-muscle strength.24 Ventouse delivery is less traumatic than forceps, but its use has not been shown to be associated with a reduced incidence of UI or neuromuscular damage.

Symptoms of urogenital atrophy are a manifestation of oestrogen withdrawal following the menopause, and may appear many years after the last menstrual period.1 Oestrogen deficiency following the menopause is known to cause atrophic changes within the urogenital tract2and is associated with urinary symptoms. The role of oestrogen replacement in the treatment of these symptoms of urogenital atrophy has still not been clearly defined despite several randomized trials and widespread clinical use. This chapter presents an overview of the pathogenesis and management of urogenital symptoms and the role of oestrogen replacement therapy.

In addition to oestrogen receptors, both androgen and progesterone receptors are expressed in the lower urinary tract, although their role is Less clear. Progesterone receptors are expressed inconsistently, having been reported in the bladder, trigone and vagina. Their presence may be dependent on oestrogen status. In addition, whilst androgen receptors are present in both the bladder and urethra, their role has not yet been defined.

Our use of the term or terms Vaginal Lawsuit is for descriptive purposes only. There is no relationship between the owners of this website and the maker of the product discussed in this post. Our use of the words Recall, Class Action Lawsuit and other similar words related to an event do not necessarily mean that this event has occurred. Refer to the website of the United States Food and Drug Administration for information on drug or medical device recalls. If a Class Action Lawsuit is formed in relation to the product discussed in this post we will provide that information at the time the Class Action is formed. A Class Action Lawsuit is not required to exist for you to file a lawsuit if you have been injured by the product discussed in this post.

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Vaginal Lawsuit

Honor Those with Cerebral Palsy during National Disability Employment Awareness Month

Birth injuries such as cerebral palsy are a life-long condition. So many adults who were born with cerebral palsy must cope with it as they live their lives, maintain families, and work full-time.

With the U.S. Labor Department celebrating October as National Disability Employment Awareness Month, we thought it would be appropriate to take a moment to honor cerebral palsy patients who contribute so much to the workforce.

Cerebral palsy is a term used for a group of conditions that are caused by injuries or abnormalities of the brain and nervous system that most often occur while the baby is still in the womb. Many times, cerebral palsy can develop due to medical negligence.

Severe cases of cerebral palsy often require regular medical assistance and can significantly hamper one’s ability to move. However, other cases may be much more manageable and allow the individual to live a mostly independent and self-sufficient life, which may include pursuing a full-time career.

National Disability Employment Awareness Month was created to help appreciate the work that disabled individuals do in the workplace every day that may otherwise go unnoticed, said Kathy Martinez, the assistant secretary of labor for disability employment policy.

“Return on investment means hiring the right talent,” said Martinez. “Workers with disabilities represent all skill sets and are ready to get the job done. This year’s theme focuses on improving employment opportunities that lead to good jobs and a secure economic future for people with disabilities and the nation as a whole.”

National Disability Employment Awareness Month also attempts to instill ideas of creating a welcoming and inclusive workplace for people with disabilities so they can gain dignity, respect and self-determination through their profession.

The history of National Disability Employment Awareness Month dates back to 1945, when Congress enacted a law declaring the first week in October each year “National Employ the Physically Handicapped Week.” By 1988, Congress expanded it to the full month of October and adjusted the name accordingly. The U.S. Department of Labor’s Office of Disability Employment Policy has handled awareness responsibilities for the month since 2001.

If you or a loved one have a child who suffered a birth injury and now suffers from a form of cerebral palsy that may have been caused bymedical malpractice or negligence, it may be worth considering a birth injury lawsuit. Speak to a birth injury lawyer at Sokolove Law today to learn more about the legal options that may be open to you.

Cerebral Palsy

How Small is an Asbestos Fiber?

We hear a lot about how mesothelioma and other asbestos-related diseases are caused by “microscopic” asbestos fibers. Easily inhaled, these tiny spear-like fibers of death become embedded into the delicate linings of the lung where, over time they can lead to scarring and eventually, mesothelioma cancer.

But how small is small?

This old advertisement from the infamous asbestos leader Johns-Manville shows how impossibly small asbestos fibers are: over 1500 of them bundled together are smaller than a human hair.

What is perhaps more astonishing then the relative size of asbestos fibers is the fact that their size was once a selling point for the global asbestos industry.

Asbestos

HUD Charges Landlords with Discriminating against Cerebral Palsy Child

The U.S. Department of Housing and Urban Development is getting involved in an unfortunate case of potential discrimination against a mother with a child suffering from cerebral palsy.

HUD officials announced this week that they have charged the landlords of an Iowa apartment building with violating the Fair Housing Act after refusing to properly accommodate the family, which has a seven-year-old daughter who suffered the childbirth injury.

As part of her treatment, the girl had previously received a Labrador retriever as a medically-prescribed emotional support animal. However, when the mother and daughter moved into an apartment owned by John and Nancy Meany, the landlords refused to modify a “no pets policy” for the apartment.

Despite the mother’s ability to provide documentation of the need for the dog to live with her daughter from her pediatrician and therapist, the landlords still refused to allow the dog unless they received a $200 deposit and a $25 monthly rent increase.

The mother and daughter felt the need to move, and eventually did so to another apartment that cost more and was farther away from the daughter’s school.

“Threatening parents with eviction for requesting an emotional support animal for a child with disabilities or charging more for having one is against the law,” said John Trasviña, the HUD assistant secretary for fair housing and equal opportunity. “HUD is committed to ensuring that landlords comply with fair housing laws and provide the accommodations that may be necessary for tenants with disabilities to have the same opportunities to enjoy their homes.”

According to the HUD’s Fair Housing Act, it is “unlawful for landlords to refuse a reasonable accommodation in their rules, policies, practices, or services when needed to provide persons with disabilities an equal opportunity to use or enjoy a dwelling.” Landlords are also not allowed to “impose different rules and restrictions” under such circumstances.

While this is a very unfortunate and sad situation, hopefully the HUD’s intervention will help this family get the help they need. Regardless, this situation shows the difficulties – and expenses – that come with caring for a child with a birth injury. If you would like to pursue a cerebral palsy lawsuit against the doctors who caused your child’s birth injury, contact a birth injury attorney at Sokolove Law today.

Cerebral Palsy

Increased Cancer Risk for 9/11 First Responders, Says Study

As the nation prepares to reflect upon the 10th anniversary of the 9/11 terrorist attacks, a new report suggests a link between exposure to toxic chemicals released after New York’s World Trade Centercollapsed and the development of cancer in firefighters who toiled at ground zero.

The study, released in the British medical journal The Lancet, found that 9/11 firefighters are 19 percent more likely to develop cancer than those who were not at the Trade Center wreckage, according toThe New York Times.

Study leader Dr. David J. Prezant said the findings indicate an “increased likelihood for the development of any type of cancer” but noted that they were far from conclusive.

Toxic substances found at the site of the 9/11 attacks, such asasbestos and jet fuel, can trigger diseases that may take decades to develop, such as mesothelioma.

A portion of New York City was covered by a cloud of fine powder after the towers fell. A study released after the terrorist attacks by the Virginia firm HP Environmental reported that the powder creating this toxic cloud contained asbestos. In fact, the asbestos particles were so pulverized in the explosion that most were smaller than what could be detected by the EPA’s standard testing method. After adjusting the test to check smaller fiber concentrations, the study concluded that there was an “overwhelming concentration” of the ultrafine asbestos particles.

The 9/11 first responders, including firefighters, police, and other emergency personnel, “were exposed to a whole soup of carcinogens,” said Dr. Philip J. Landrigan of. Dr. Landrigan is the director of environmental and occupational medicine at Mount Sinai School of Medicine in Manhattan and a leading expert on asbestos toxicity. He is also the principal investigator of a related report published in The Lancet on the health effects of the attacks on recovery and rescue workers.

However, Dr. James Melius, administrator of the New York StateLaborers’ Health and Safety Trust Fund and a peer reviewer of the firefighter study, warned that it “would probably not be enough to persuade federal officials to include cancer as one of the diseases covered under the Zadroga Act.”

The James Zadroga 9/11 Health and Compensation Act of 2010 (H.R. 847) was called into law by President Obama in 2010 and it statesthat those who have 9/11 related health conditions may be eligible for health care under this law.

If you were diagnosed with mesothelioma and suspect you wereexposed to asbestos at ground zero, you may be entitled to financial compensation. To learn more about your legal options regarding a possible mesothelioma settlement, please contact an asbestoslawyer.

Asbestos

International Mesothelioma Program New Research

The International Mesothelioma Program at Brigham and Women’s Hospital and Harvard Medical School in Boston continue to make progress in malignant mesothelioma research. The scientists and doctors involved with the project are looking for information that will lead to better adjuvant therapies for the rare and deadly disease. Adjuvant therapies are treatments given to help boost the effectiveness of other treatments. In the case of malignant mesothelioma, the term “adjuvant therapies” typically refers to treatments that are administered to patients after they have had tumors surgically removed.

In a recent study, scientists used mice to test potential adjuvant therapies. Human mesothelioma cells were introduced into the test mice, allowed to metastasize (to grow), then surgically removed. This procedure turned the mice into workable test subjects for testing ne mesothelioma adjuvant therapies.

One of the therapies researchers studied on the mice was “intracavitary chemotherapy,” which means applying the chemotherapy drug, paclitaxel, into the cavity of the body around the site where the tumor has been removed just prior to closing the incision. The results of this test on the test mice were encouraging.

In a report published in the Annals of Thoracic Surgery, “Paclitaxel-laded Expansile Nanoparticles in a Multimodal Treatment, Model of Malignant Mesothelioma,” the researchers state: “Treatment with [paclitaxel] improved overall survival in the setting of [the surgery], suggesting that [it] merits further evaluation for intracavitary drug delivery following the surgical resection of malignant mesothelioma.” What this means is that this particular adjuvant therapy may be successful in the survival of mesothelioma patients.

Advancements such as these are very important to patients of malignant mesothelioma, as the cancer is serious and fatal.

For those who have been diagnosed with mesothelioma cancer that can be linked toasbestos exposure caused by a product or former employer, you may be entitled to financial compensation. Contact an experienced mesothelioma attorney to learn more about your rights, and to see if pursuing a mesothelioma settlement is in your best interest.

Mesothelioma